Apoptosis is recognised as being dysregulated in AML, and overexpression of many anti-apoptotic proteins, such as B-cell lymphoma 2 (Bcl-2), BCL-XL, and myeloid cell leukaemia-1 (MCL-1), has been associated with poor outcomes in AML [5]. This evidence concerns the gene BCL2L1 and acute myeloid leukemia.