Those cell lines covered a spectrum of cytogenetic variations and mutational backgrounds and included the Kasumi-1 cell line (from a 7-year-old boy with AML FAB M2 (in the second relapse after bone marrow transplantation) with the t(8;21) translocation and a KIT mutation N822), MV4-11 cell line (from a 10-year-old boy with AML FAB M5 and t(4;11) translocation and an FLT3 internal tandem duplication), and the CMK cell line (originating from a 10-month-old boy with Down’s syndrome with AML M7 at relapse) [9]. The gene discussed is KIT; the disease is acute myeloid leukemia.