The comparison of gene expression levels in germinal center B-cell-like (GCB) DLBCL (SUDHL6) and ABC DLBCL cell lines with MyD88 (SUDHL4 and U2932) vs. MyD88L265P ABC DLBCL (OCI-Ly3, OCI-Ly10, HBL1, and TMD8) revealed consistently higher expression of genes BATF, LGALS3, NFKBZ, and CD44 in cells bearing the MyD88 L265P mutation (Figure 3A), which was not the case for the other most significantly upregulated genes (Figure S3A). Here, LINC00458 is linked to diffuse large B-cell lymphoma.