In normal B cells, NFKBIZ expression is induced by BCR or TLR stimulation [117] and an increase in the NFKBIZ transcript and IκBζ protein was demonstrated due to constitutive oncogenic NF-κB signaling in MyD88L265P- or CARD11L244P-expressing lymphoma cells [45]. The gene discussed is NFKBIZ; the disease is lymphoma.