NFKB1 and neoplasm: Recently, single-cell transcriptomics analyses have explored the molecular pathways that regulate the maturation of intratumoral conventional type 1 dendritic cells (cDC1s), which is critical for antitumor immunity, and have demonstrated the dynamic reprogramming of tumor-infiltrating cDC1s by NF-κB and IFN signaling pathways [93].