β-Amyloid (Aβ) and tau peptides as well as neurofilament light chain (NF-L) as neurodegeneration indicators [4] can be detected in the cerebrospinal fluid (CSF) of patients to allow differential diagnosis of dementia types and pathologies, e.g., typical AD, non-AD tauopathies, hippocampal sclerosis or mixed brain pathologies [3]. The gene discussed is NEFL; the disease is tauopathy.