Moreover, using least absolute shrinkage and selection operator (LASSO) analyses, we successfully developed a novel LLPS-related index based on six LRGs (including FUS, CBX2, TPX2, TAZ, USH1C, and AXIN1) that performed well in predicting the BCR-free survival (BCRFS) of patients with PCa. Here, CBX2 is linked to posterior cortical atrophy.