ASPH and metastatic malignant neoplasm in the lymph nodes: In multivariate Cox regression analysis, ASPH was indicated to be a novel independent prognostic factor of OS in the NACT patient group (HR = 2.804; 95% CI: 1.468–5.356; p = 0.002), accompanied by other prognostic factors including lymph node metastasis (p = 0.028) and distant metastasis (p = 0.019).