Epigenetic dysregulation of DNA in OSAS was shown by aberrant methylation of the formyl peptide receptor (FPR) 1, 2, 3 genes, and FPR1 overexpression and the deficiency of FPR2 and FPR3 were associated with OSAS and its severity as well as with the development of diabetes mellitus and cardiovascular diseases. This evidence concerns the gene FPR2 and diabetes mellitus.