Furthermore, members of the Ikaros family of zinc-finger (IKZF) proteins have previously been associated with ALL susceptibility, and since IKZF2 transcription factor, one of the potential targets of miR-612, is involved in the regulation of lymphocyte development, the effect of the mutant allele rs12803915 A in the regulation of miR-612 could explain an association with ALL risk, but studies in different cohort of patients might be performed to confirm such results [60,84,85]. Here, IKZF2 is linked to acute lymphoblastic leukemia.