A recent study identified miRNAs such as miR-125b-5p, miR-155-5p, miR-181a-5p, and miR-19a-3p and coding genes such as BCL2, TP53, KIT, and MYB with the highest number of interactions in several forms of leukemia and other hematological malignancies, including chronic lymphocytic leukemia (CLL) and myelodysplastic syndromes [56]. The gene discussed is TP53; the disease is B-cell chronic lymphocytic leukemia.