RUNX1 and acute lymphoblastic leukemia: For instance, Schotte et al., when evaluating 397 miRNAs, found that these genes cluster in specific expression patterns, which are useful to differentiate among mixed-lineage leukemia (MLL)-rearrangements, TEL-AML1-positive, E2A-PBX1-positive, and hyperdiploidies, but not BCR-ABL1-positive ALL and “B-other” ALL (lacking recurrent fusion genes) [110].