Moreover, miR-29c-5p has been considered to be the best discriminator between childhood T- and B-ALL, due not only to its upregulation in T-ALL, but also because among the potential targeted genes of this miRNA are some participating in ALL development, such as AFF1, KMT2A, and ELK4 [126]. This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.