Figure 2 summarizes these mechanisms. The first pro-atherosclerotic mechanism is an increased migration of macrophages and an augmented formation of foam cells in cholesterol plaques [151,152]. In a trial involving mice supplemented with either choline or TMAO, Park et al. found that scavenger receptor-A (SR-A) and CD36, two macrophage receptors associated with atherosclerosis, were both increased when compared to control mice [153]. Here, CD36 is linked to atherosclerosis.