In fact, LPS induce endothelial dysfunction, increase oxidative stress through production of reactive oxygen species (ROS), and produce several pro-inflammatory cytokines, such as TNF-α, interleukin-1 (IL-1), interleukin-6 (IL-6), and interleukin-8 (IL-8) [26,27,28]. Here, IL6 is linked to endothelial dysfunction.