Skarie & Link (2009) [59] reported that a mutant zebrafish line with silenced forkhead box C1 (foxc1) presented altered hyaloid vasculature and arteriovenous defects, as well as ocular hemorrhages and increased vascular permeability, indicative of the disruption of basement membrane integrity, which is related to the glaucoma development process. This evidence concerns the gene FOXC1 and glaucoma.