Furthermore, zebrafish have greatly improved the understanding of diseases of posterior structures of the eye related to several syndromes, such as Leber’s congenital amaurosis (LCA), modeled by Minegishi, Nakaya, & Tomarev (2018) [47] through a cct2 mutant zebrafish line, whereas Stiebel-Kalish et al. (2012) [48] studied the same disease with a Gucy2f zebrafish knockdown line; Stargardt’s disease, Bardet–Biedl syndrome (BBS), Usher syndrome, Joubert syndrome, Meckel-Gruber syndrome, and Senior-Loken syndrome (Table 2). The gene discussed is CCT2; the disease is Leber congenital amaurosis.