To better understand the characteristics of the hiPSC-SCs derived from the modified MHH protocol, we further used primary adult human Schwann cells (ahSCs) as a control in ICC for the Schwann cell markers, SOX10, S100B, p75NTR, GFAP, and CDH19, commonly discussed to be a marker for the precursor stage (Figure 4). This evidence concerns the gene S100B and intrahepatic cholangiocarcinoma.