There were a few genes that were only significantly associated with a single craniosynostosis phenotype, including HOXB4 (sagittal), IRX2 (sagittal and male sagittal), MESI1, MEIS2 (metopic), IRX1 (male metopic), ALX1 (metopic and male metopic), HOXB2 (lambdoid), and HOXB3 (lambdoid and male lambdoid). Here, ALX1 is linked to craniosynostosis.