PDCD1 and nonpapillary renal cell carcinoma: We analyzed the relationship between PD-1/PDCD1 expression and immunotherapy response as well as survival in ccRCC patients receiving anti-PD-1 therapy in the CheckMate cohort derived from Braun et al. In our study, patients were divided into a high PD-1/PDCD1 expression group and a low PD-1/PDCD1 expression group according to the median expression level.