Interestingly, among multiple CRF genes, only SMARCA2, SMARCB1, ACTL6B and KDM5C have been previously associated with epilepsy, and some other members of this cluster (e.g., SMARCC1, SMARCC2, SMARCA4 and WRD5) are only cursorily mentioned among epilepsy candidate genes [62,63,64,65]. Here, KDM5C is linked to epilepsy.