Additionally, there is an imbalance in the analysis of CXCR4 expression within various renal tissues: while a large body of evidence is available for clear cell renal cell carcinoma (ccRCC), there is a lack of information on CXCR4 expression in benign renal tissue, including oncocytomas and angiomyolipomas, as well as the differential expression of CXCR4 in ccRCC in comparison to other malignant subtypes. This evidence concerns the gene CXCR4 and clear cell renal carcinoma.