On the other hand, by inhibiting the expression of TRPV4, it further suppresses Ca2+ influx into cells, lowers the Glu level in brain tissue, inhibits the expression of aquaporins, reduces water entry into astrocytes after cerebral ischemia, improves cell swelling, and treats cerebral ischemic edema. The gene discussed is TRPV4; the disease is Cerebral ischemia.