NR1H4 and hepatocellular carcinoma: In the present study, to investigate the effect of C-terminal truncated HBx on the progression of hepatocarcinogenesis in FXR deficiency and preliminarily analyze its mechanism, we demonstrated that C-terminal truncated X protein (HBx C40) exhibits distinct profiles concerning their regulation of cell growth and hepatocellular carcinoma development in FXR deficiency.