For example, Sp1 induces expression of multiple miRNAs in lung cancer cells (miRNA-3194-5p, miRNA-218-5p, miRNA-193-5p, miRNA-182-5p and miRNA-135-5p), [74] miRNA-200 in breast cancer cells [75], and miRNA-365 in Hela cells [76]. Here, SP1 is linked to lung cancer.