By Gene Set Enrichment Analysis (GSEA), we revealed that DEGs of PARP1-KO versus WT cells (Figure 4B) were present in the processes associated with DNA base excision repair, oxidative phosphorylation, proteasome, ribosome, protein processing in endoplasmic reticulum, ribosome biogenesis in eukaryotes, microRNAs in cancer, antigen processing and presentation, transcriptional misregulation in cancer, focal adhesion, protein export, RNA transport, metabolism of xenobiotics by cytochrome P450, and other processes (Table S1). This evidence concerns the gene PARP1 and cancer.