OLR1 and endothelial dysfunction: Thus, it has been described that LOX-1 and oxLDLs are essential modulators of endothelial dysfunction, which is characterized by the increase in the secretion of pro-inflammatory cytokines, an increase in the ROS levels, the expression of pro-coagulants molecules, expression of adhesion molecules, such as I-CAM, V-CAM, E-selectin, and P-selectin, and an increase in endothelium permeability [11,12,13].