Levels of CCL16 (+9.28%, p = 0.0069) (Figure 2c) and soluble TNF receptor 2 (sTNF-RII, +8.78%, p = 0.0425) (Figure 2d) were significantly increased in the plasma of fast ALS when compared to slow ALS and/or controls. This evidence concerns the gene CCL16 and amyotrophic lateral sclerosis.