In an animal model was verified that dietary ferulic acid supplementation suppresses blood glucose elevation, body and hepatic lipid accumulation, body weight gain, and inflammatory cytokines (IL-6 and TNF-α) in high-fat diet-induced obese mice, suggesting that ferulic acid could be helpful in lowering the risk of high fat-diet induced obesity and obesity-related metabolic syndromes [1]. Here, TNF is linked to obesity due to melanocortin 4 receptor deficiency.