Five hundred and sixty-seven miRNAs associated with nine autophagy proteins (ULK1, ATG16L1, MAP1LC3B, PRKAA1, ATG12, ATG 14, ATG5, mTOR and BECN1) were identified, of which sixty-two are accompanied by thyroid cancer, and only miR-125b is associated with the autophagy modulation in this pathology. The gene discussed is PRKAA1; the disease is thyroid cancer.