These tests allow us to simultaneously examine all the above-mentioned genes (BRCA1, BRCA2, PALB2, ATM, CHEK2, BARD1, BRIP1, RAD51C, RAD51D, TP53, PTEN, MSH2, MSH6, MLH1, PMS2, EPCAM, CDH1, NF1, STK11) associated with a certain family cancer phenotype, helping in the differential diagnosis of HBOC. This evidence concerns the gene BRCA1 and cancer.