The leukemic cells of the other six PML::RARA-negative AML cases with APL-like morphological features, except the KMT2A-positive patient (due to the specific tumor biology), had more or less a typical myeloid immunophenotype, with strong expression of pan-myeloid antigens (CD33, CD13, MPO). This evidence concerns the gene MPO and acute promyelocytic leukemia.