In our study, 94.1% of patients demonstrated classic APL with t(15;17)(q24;q21)/PML::RARA, 1.9% carried cryptic PML::RARA and 1.5% had t(5;17)(q35;q21)/NPM1::RARA variant (255, 5 and 4 of 271, respectively). This evidence concerns the gene NPM1 and acute promyelocytic leukemia.