However, rare cases of RARA-negative AML with APL-like features were also described featuring RARB or RARG [16,37,38,39,40,41,42,43,44,45,46,47], KMT2A fusions [33,48,49] and various other genetics [15,33,50,51,52] (see Table S4). The gene discussed is KMT2A; the disease is acute promyelocytic leukemia.