These systemic syndromes can be caused by a series of genes, including NYX, CACNA1F, GRM6, and LRIT3, responsible for congenital stationary night blindness (CSNB) [29,30,31,32]; COL2A1, COL11A1, COL9A1, and COL9A2, responsible for Stickler syndrome [33,34,35,36]; and FBN1, responsible for Marfan syndrome [37,38]. The gene discussed is COL2A1; the disease is Stickler syndrome.