In the present study, we were able to detect the contribution of the GRIN2A, GRIN2B, GRM8, SLC1A2, and SLC17A7 genes of the glutamatergic system to determining the clinical heterogeneity of schizophrenia, which is important for the prognosis and outcome of the disease. The gene discussed is GRIN2A; the disease is schizophrenia.