CCDC80 and muscle tissue disorder: Our results suggest that a 13 gene signature (COL6A3, COL1A2, MFAP5, DCN, PDGFRB, LUM, IGFBP4, EMILIN1, CCDC80, FAP, CDH11, THBS2, and ELN) is altered in in vitro and in vivo HIBM models as well as in many other muscular disorders.