In addition, three “spliceosomal” and five “non-spliceosomal” genes, PRPF40A, ESS2, HABP4, EEF1D, CCDC155, VPS29, PLPPR4, and GATD3A, have been associated with various types of neurodevelopmental and neurodegenerative phenotypes, including schizophrenia, Alzheimer’s, and Parkinson’s. Here, ESS2 is linked to Parkinson disease.