With FRA10AC1 being well-connected by three binary interactors, namely VPS29, GATD3A, and EEF1D, to APP (amyloid β A4 precursor protein) (Figure 4), the previously reported information characterizing two FRA10AC1 SNPs biomarkers of Alzheimer’s disease [30] is further supported. The gene discussed is APP; the disease is early-onset autosomal dominant Alzheimer disease.