CD4 and autoimmune thrombocytopenic purpura: The expression of miRNAs related to helper T or Treg cells was found to regulate the Th17/Treg ratio in CD4+ T cells. Lower levels of miR-99a were observed in ITP patients compared with healthy controls, while higher levels of miR-182-5p and miR183–5p were seen among ITP patients. Positive correlation between increased percentage of Treg and decreased levels of miRNA-99a was also noted in ITP patients.