However, Hearl et al. found an only 8% risk of breast cancer by the age of 40 among women with STK11/LKB1 pathogenic variants, with a non-significant difference (log-rank test of difference = 0.62; p = 0.43) between carriers of STK11/LKB1 mutations compared to non-carriers [136]. This evidence concerns the gene STK11 and breast cancer.