RAD51C and breast carcinoma: In an association analysis that used a panel of 34 putative susceptibility genes to perform sequencing on samples from 60,466 women with breast cancer and 53,461 controls, pathogenic germline variants in RAD51C (OR = 4.83; 95% CI: 0.52–45.2) and RAD51D (OR = 1.76; 95% CI: 0.38–8.17) were both found to be associated with the risk of developing breast cancer before 40 years of age [118].