ESR1 and breast cancer: In the 40–49 age range, the probability of having an estrogen receptor positive (ER+) BC is significantly higher (OR = 1.50, 95% CI: 1.36–1.67, p < 0.001) although the probability of having a triple-negative breast cancer (TNBC) is lower compared to Americans (OR = 0.79, 95% CI: 0.71–0.88, p < 0.001) [40].