PGR and breast cancer: In the multivariate analysis, cytoplasmic HSP70 immunoreactivity/macrophage infiltration (p = 0.011), as well as the pathological T factor (p = 0.0053), PR (p = 0.025), and HER2 (p = 0.026), were identified as independent prognostic factors for disease-free survival, while no factors were identified as independent prognostic factors for breast-cancer-specific survival with a relative risk over 1.0 (Table 3).