However, Fn can not only promote EMT by altering tumor cell metabolism leading to metastasis, but also increases miR-155-5p and miR-205-5p expression through activation of innate immune signaling to suppress alcohol dehydrogenase 1B (ADH1B) and transforming growth factor β receptor 2 (TGFBR2) expression. This evidence concerns the gene FN1 and neoplasm.