VCAN and neoplasm: Microarrays identified 25 transcripts over-represented in KrasMUT tumor cells, and a proteomic screen of tumor cell-conditioned media detected 226 proteins secreted > 10-fold by KrasMUT over KrasWT cells, with the glycoprotein versican (VCAN; encoded by the human/murine VCAN/Vcan genes) emerging from both screens and withstanding validation (Figure 4A–E and Figure S12D,E, Table S2, and Data S1).