The mechanisms for the antiproliferative effect of SSAs seem to be related to the activation of SSTRs, leading to induction of G1 cell cycle arrest and apoptosis, particularly via SSTR2, and to the inhibition of tumour angiogenesis and mitogenic circulating growth factors, although the antiproliferative effect of SSAs does not impact overall survival [156]. Here, SSTR2 is linked to neoplasm.