This observation is in accordance with our previous findings, which showed that the vast majority of luminal breast carcinomas (93.7%) contained 5–35% Ki67 positive tumor cells and that SA-β-gal positivity is inversely correlated with Ki67 positivity, supporting the notion that senescent SA-β-gal positive tumor cells are cell cycle arrested [38]. This evidence concerns the gene MKI67 and breast carcinoma.