ENOSF1 and colorectal carcinoma: Rosmarin et al. (European ancestry; UK) reported a significant association of the G allele of the ENOSF1 rs2612091 SNP (c.496-227G>A; intron) with overall toxicity and severe HFS in 940 patients with CRC (stages II–III) treated with capecitabine ± bevacizumab (OR = 1.59; 95% CI = 1.39–1.79; p = 5.28 × 10–6 and OR = 1.57; p = 2.94 × 10–6, respectively, both for G vs. A) [21].