As for the DPYD rs1801265 SNP (c.85T>C; missense; p.Cys29Arg), Varma et al. (Asian; India) reported that patients carrying the C allele showed an increased risk of thrombocytopenia (OR = 2.40; 95% CI = 1.18–5.10; p = 0.010 for CT/CC vs. TT), diarrhea (OR = 2.70; 95% CI = 1.80–4.00; p = 0.040 for CT/CC vs. TT), and HFS (OR = 2.30; 95% CI = 1.80–4.00; p = 0.020 for CT/CC vs. TT) during CAPOX treatment [28]. The gene discussed is DPYD; the disease is Hand-foot syndrome.