AFP and neoplasm: Several promising CAR-T cell tumor targets were identified, including Glypican-3 (GPC3), alpha-fetoprotein (AFP), NK group 2 member D ligand (NKG2DL), Mucin 1 glycoprotein 1 (MUC1), Epithelial cell adhesion molecule (EpCAM), Claudin18.2 (CLD18), CD147, CD133, HBV surface protein, and c-MET [37,38,39].