In a recent systematic review and meta-analysis including patients with extramammary Paget’s disease, the expression rates of hormones receptors were 12% (95% CI = 0.03–0.36) for estrogen receptors (ERs), 9% (95% CI = 0.03–0.25) for progesterone receptors (PRs), and 40% (95% CI = 0.34–0.47) for androgen receptors (ARs) [118]. Here, ESR1 is linked to glycogen storage disease VI.