It is also worth noting that among the upregulated genes that we found, it is the first time, to our knowledge, that FBLN5, CACNA2D2, M1AP, TPPP3, and TSPAN32 are mentioned to be upregulated in AML, indicating that perhaps other pathways are also likely implicated in the disease. The gene discussed is TPPP3; the disease is acute myeloid leukemia.