XPC and osteosarcoma: In CDDP-treated patients, GSTM1, GSTT1 [18,38,39,40,41,42], and GSTP1 c.313A>G [38,39,41,43] were seen in pediatric solid or adult testicular tumors with controversial results in ototoxicity, while XPC c.2815A>C SNV influenced ototoxicity in osteosarcoma patients [44].