The DNA lesion induced by CDDP can be removed through the nucleotide excision repair (NER) pathway [25], mediated by the xeroderma pigmentosum (XPC, XPD, and XPF) [26,27] and excision repair cross-complementation group 1 (ERCC1) genes [28], as well as by the mismatch repair (MMR) pathway, mediated through proteins encoded by MutL homolog 1 (MLH1) [29], MutS homolog 2 (MSH2) [30], MutS homolog 3 (MSH3), and exonuclease 1 (EXO1) genes [29]. The gene discussed is MLH1; the disease is xeroderma pigmentosum.