Immunohistochemical analysis of normal and cancer tissue applying the commercially available tissue microarray TMA MC809, followed by the scoring of cells positively stained for the La protein, indicated the overexpression of the La protein in neuroblastoma, nephroblastoma and glioblastoma tissue compared to normal cerebrum, cerebellum, and kidney tissue (Figure 9a,b). The gene discussed is SSB; the disease is glioblastoma.