BAP1 and Down syndrome: When we focused on tumors potentially associated with BAP1 syndrome [7], we found 84 (7.4%) cases of cutaneous basal cell carcinoma, 49 (4.3%) of renal cell cancer, 46 (4.0%) of melanoma (42 cutaneous melanoma, 4 uveal melanoma), and 11 (1.0%) of hepatocellular carcinoma.