Also, an earlier report demonstrated that miR-483 targets TIMP2 and PDGF-β leads to suppressed CCl4-mediated liver fibrosis in mice [35], and miR-483 also targets TGFβ which is involved in fibrogenic responses in pulmonary arterial hypertension (PAH) [51]. The gene discussed is PDGFB; the disease is Hepatic fibrosis.