At the same time, the overexpression of miR-483 increased FASN and ACC in HepaRG, HepG2, and SK-Hep1 cells compared with NC transfected cells (Supplementary Figure S1B), suggesting that miR-483 dysregulates lipogenic signaling in hepatocytes and HCC cells. The gene discussed is FASN; the disease is hepatocellular carcinoma.