The associations among the independent factors of baseline eNAMPT, including colonic pathology, TC and NLR, were as follows: baseline age, eNAMPT levels, and polyp size were associated with colonic polyp pathology ( Supplementary Table S3); baseline eNAMPT and HDL-C levels, platelet count, and polyp size and number were associated with baseline TC levels ( Supplementary Table S4); and baseline eNAMPT and HS-CRP levels were associated with baseline NLR ( Supplementary Table S5). Here, CRP is linked to polyp of colon.