POMC and Cushing syndrome due to macronodular adrenal hyperplasia: Some of the most common presentations include Cushing’s syndrome, acromegaly, and hypoglycemia caused by the secretion of adrenocorticotrophic hormone (ACTH), growth hormone-releasing hormone (GRHR), and insulin-growth factors (IGF), respectively [12,13,14,15,16,17,18,19,20].