Furthermore, mutations in a variety of genes known to be associated with myelodysplastic syndrome (MDS) have been incorporated and include genes such as ASXL1, BCOR, EZH2, RUNX1, SF3B1, SRSF2, STAG2, U2AF1, and ZRSR2. The gene discussed is ASXL1; the disease is myelodysplastic syndrome.