However, according to Jahwar et al., KIT D816 mutations are more frequent than previously reported, as alternative mutations of KIT at position 816 such as D816H or D816Y may be found in a proportion (20%) of KITD816V-negative patients, leading to an overall incidence of KIT D816 mutations in about 90% of MCL patients [5]. This evidence concerns the gene KIT and mantle cell lymphoma.