In non-HPV-associated HNSCC tumours, a better OS was noted in patients with high Foxp3+ TILs (HR 0.80; 95% CI: 0.70–0.92) and similar dependences were seen for DFS (HR 0.77; 95% CI: 0.57–1.02) and LRC (HR 0.92; 95% CI: 0.81–1.04) [70,71]. The gene discussed is FOXP3; the disease is head and neck squamous cell carcinoma.