Moreover, it has been proven that STING signalling promotes STING-mediated interferon response in non-tumour cells to activate CD56dim/CD16bright NK-dependent cytotoxicity, induces apoptosis of malignant B cells and remodels the TME by antagonizing myeloid-derived suppressor cell (MDSC) expansion in nasopharyngeal carcinoma, and enhances the presentation of TAAs by DCs and cross presentation to CD8+ T cells [103,104,105,106]. This evidence concerns the gene CD8A and neoplasm.