The study results indicate that CRT induces NK cell activation ligand (ULBP2) and adhesion molecules (ICAM-1, -2 and -3) on HNSCC, leading to enhanced cytotoxicity of NK cells against HNSCC; this correlated with increased NK cell infiltration and better overall survival in patients with HNSCC [294]. Here, ULBP2 is linked to head and neck squamous cell carcinoma.