High levels of CD8+ TILs were associated with a better prognosis in hypopharyngeal cancers (HR 0.43; 95% CI: 0.30–0.63), and in both HPV-related tumours and non-HPV-associated tumours (HR 0.39; 95% CI: 0.16–0.93 and HR 0.40; 95% CI 0.21–0.76, respectively) [63,67,68,69]. The gene discussed is CD8A; the disease is neoplasm.