The use of this 80 kDa polymer was associated with the enhanced production of anti-tumour inflammatory/Th1 cytokines, as well as a higher expression of immune-stimulating cytokines, such as IFN-γ and reduced excretion of immunosuppressive cytokines, such as IL-10 in HNSCCs cell lines [579,584,585]. The gene discussed is IFNG; the disease is neoplasm.