Later, in another study, serum specimens were analyzed for four tumor markers, including MUC16, CA72-4, CA15-3, and M-CSF, in healthy women (n = 100), benign ovarian carcinoma (n = 45), and invasive epithelial ovarian carcinoma (N = 55) to evaluate biomarker potential in combination with artificial neural network (ANN) analysis [191]. The gene discussed is MUC16; the disease is neoplasm.