Overexpression of MUC1 and MUC3 was reported in 90% of BC cases and found to be associated with high local recurrence and lymph node metastasis [166], suggesting the application of a MUC1-MUC3 detection panel for the prediction of local recurrence and lymph node metastasis. The gene discussed is MUC1; the disease is metastatic malignant neoplasm in the lymph nodes.